a89630731的翻翻部落格

<<原文-1>>

A herpes link to Alzheimer’s

Multiple studies suggest that there’s a link between several common herpes viruses and the onset of Alzheimer’s disease.

  In one study, at least 70 per cent of elderly people, including those with Alzheimer’s, had HSV-1 (the herpes simplex virus that causes cold sores) in their brains. Moreover, those who had both HSV-1 and the APOE e-4 gene, which has already been linked to Alzheimer’s, were much more likely to develop the brain disease than those without either.

  While this study does not prove that herpes viruses cause Alzheimer’s, another study found that patients infected with herpes who had sought antiviral treatment (using drugs such as acyclovir) cut their risk of developing dementia later in life by a factor of ten.

<<譯文>>

皰疹與罹患阿茲海默症的風險

許多研究結果認為，部分常見的皰疹病毒和初期階段的阿茲海默症互為相關。

    在一份相關研究中指出，至少70%的年長者，包括阿茲海默症患者在內，腦內都發現存在HSV-1病毒 (單純皰疹病毒，會造成患部起水泡)。此外，腦內存在HSV-1病毒或是攜帶APOE e-4基因其中之一，這兩種人都有可能罹患阿茲海默症；然而，前兩項條件都具備者，罹患阿茲海默症的機率相對更高。

雖然，這項研究未證實皰疹病毒會直接導致阿茲海默症。不過，另一項研究則發現，皰疹患者曾尋求抗病毒治療(像是acyclovir這類，抗病毒藥物)，能降低10倍，日後失智發生的風險。

<<原文-2>>

Managing gut bacteria and diet may alleviate anxiety

  People who experience anxiety symptoms might be helped by taking steps to regulate the microorganisms in their gut using probiotic and non-probiotic food and supplements, and changing their diet. Gut bacteria may regulate brain function via the ‘gut-brain axis,’ according to a review of 21 studies involving a total of 1503 people.

  Of the 14 studies that tested probiotics to regulate intestinal microbiota, 36 per cent were effective in reducing anxiety symptoms. Six of the remaining seven studies using non-probiotic methods, such as adjusting daily diet over a set period, found an 86 per cent rate of effectiveness.

<<譯文>>

做好腸道菌和飲食管理能舒緩焦慮

根據21份試驗研究，共1503位受試者的參與，發現透過 ’腸-腦軸線’ （gut–brain axis），腸道菌能調節腦部運作。從調整腸道內的微生物著手，研究利用益生菌食物與非益生菌食物，以及營養補充品，改變飲食，認為有助受焦慮困擾的人，改善因焦慮引起的不適症狀。

這當中的14份研究，進行益生菌對消化道微生物叢調節的實驗，發現百分之三十六的受試者能有效降低焦慮症狀。另外7份研究中，有6份研究採非益生菌飲食，比方說，調整日常飲食一段時間等，發現百分之八十六的受試者能有效降低焦慮症狀。

<<原文-3>>

Testosterone replacement could ease COPD

  Researchers who analysed data from more than 700 men with chronic obstructive pulmonary disease (COPD) found that those who started testosterone replacement therapy (TRT) were less likely to be hospitalized for respiratory problems than those who didn’t; this effect was greatest in men 66 and older. TRT may also slow the progression of the disease.

<<譯文>>

補充睪固酮有助舒解慢性阻塞性肺疾病不適

針對700位慢性阻塞性肺疾病(以下簡稱COPD)男性患者，分析相關數據資料，研究人員發現，COPD的男性患者中，接受睪固酮補充治療(以下簡稱TRT)者，較少出現呼吸道問題就醫的狀況，該治療效果對66歲(含)以上的男性患者尤為明顯。TRT治療對延緩COPD疾病的惡化亦同樣有效。

Nov. 2019, P. 24